Reusable Imaging Chamber
John Hayden Colvin
OVERVIEW
This ongoing undergraduate research project focuses on designing a reusable imaging chamber to replace the current single-use coverslip slide system used in microscopy. The existing setup relies on thin cover slides and silicone O-rings that are fragile, difficult to clean, and unstable on the microscope stage, often shifting out of focus. My work centers on developing a rigid, reusable frame that holds the cover glass flush while maintaining a reliable fluid seal for consistent, high-quality imaging.
HighlightS
- Identified mechanical limitations of current coverslip slide setup including instability and breakage
- Designed two reusable chamber concepts: a top-support vessel and a bottom-support vessel
- Compared designs based on ease of loading, security, cost, and microscope compatibility
- Modeled rigid frame structures to maintain optical alignment and sealing performance
- Evaluated trade-offs between quick assembly and structural stability
- Outlined future development including material selection and manufacturing methods such as machining and 3D printing
SKILLS
Parametric CAD design & iterationConcept comparison and trade-off analysisMechanical sealing system designDesign for laboratory usabilityResearch-driven engineering developmentEarly-stage design for manufacturability
External Links
ADDITIONAL CONTENTS
John Hayden Colvin
Mechanical Engineering Student & Problem Solver
I'm a detail-oriented mechanical engineering student at Rensselaer Polytechnic Institute with a 3.83 GPA and hands-on expertise in CAD software including AutoCAD, Inventor, and Siemens NX. I combine technical skills in machining, welding, and laboratory research with strong problem-solving abilities. Currently conducting undergraduate research on cytoskeletal networks while maintaining NCAA varsity athletics, demonstrating my ability to balance rigorous academic and professional commitments.
I'm a detail-oriented mechanical engineering student at Rensselaer Polytechnic Institute with a 3.83 GPA and hands-on expertise in CAD software including AutoCAD, Inventor, and Siemens NX. I combine technical skills in machining, welding, and laboratory research with strong problem-solving abilities. Currently conducting undergraduate research on cytoskeletal networks while maintaining NCAA varsity athletics, demonstrating my ability to balance rigorous academic and professional commitments.